An ERM represents glial cell proliferation between the internal limiting membrane (ILM) of the neurosensory retina and the posterior hyaloid membrane of the vitreous. It can result in vitreomacular traction (VMT) and potentially macular hole formation.
Green, Yellow and Amber: An ERM can be seen nasal to the macula extending to the disc. The membrane has a glassy appearance with folds or striations radiating from it
Red, Deep Red and IR: Effects of the ERM are not seen in the outer retina, in this case. Longstanding ERM's create traction that may result in melanin clumping in the RPE, which can be seen with long wavelength MSI
Stereo: Some elevation or distortion can be seen in the area of traction, adjacent to the disc
OH Contrast 1
OH Contrast 2
SLO: The ERM is apparent, but the depth and extent of the traction is not
OCT: Confirms the presence of the ERM and traction adjacent to the disc
Epiretinal membranes can easily be identified with Multi-Spectral Imaging.
MSI short wavelengths are excellent at highlighting epiretinal membranes. Long wavelength MSI has shown underlying melanin clumping in the ridges of longstanding ERMs, indicating secondary RPE disruption.